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Vitamin D Effectiveness and Safety in Relation to Bone Health

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Effectiveness and Safety of Vitamin D in Relation to Bone Health. This report is based on research conducted by the University of Ottawa Evidence-based Practice Center (EPC). To review and synthesize the literature in the following areas: the association of specific circulating 25(OH)D concentrations with bone health outcomes in children, women of reproductive age, postmenopausal women and elderly men; the effect of dietary intakes (foods fortified with vitamin D and/or vitamin D supplementation) and sun exposure on serum 25(OH)D; the effect of vitamin D on bone mineral density (BMD) and fracture or fall risk; and the identification of potential harms of vitamin D above current reference intakes.


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