Vitamin K Substance . Vitamin K comprises a group of substances, which are widespread in nature and are …. bisulfite; vitamin K injection; vitamin K3 sodium bisulfite …
VITAMIN K SUBSTANCES
Vitamin K comprises a group of substances, which are widespread in nature and are an essential co-factor in humans in the synthesis of several proteins that play a role in haemostasis and others that may be important in calcium homeostasis. The K vitamins all contain the 2-methyl-1,4-naphthoquinone (menadione) moiety, and the various naturally occurring forms differ in the alkyl substituent at the 3-position. Phylloquinone (vitamin K1) is 2-methyl-3-phytyl-1,4-naphthoquinone and is widely found in higher plants, including green leafy vegetables, and in green and blue algae. The menaquinones (formerly vitamin K2) have polyisoprenyl substituents at the 3-position and are produced by bacteria. The compound menadione (formerly vitamin K3) lacks an alkyl group at the 3-position but can be alkylated in vivo in some species. Several synthetic water-soluble derivatives, such as the sodium diphosphate ester of menadiol and the addition product of menadione with sodium bisulfite, also have commercial applications (National Research Council, 1989; Gennaro, 1995; Weber & Rüttimann, 1996).
Chemical and physical data Nomenclature, structural and molecular formulae and relative molecular masses
Vitamin K (generic) Chem. Abstr. Serv. Reg. No.: 12001-79-5 Chem. Abstr. Name: Vitamin K Vitamin K1 (generic) Chem. Abstr. Serv. Reg. No.: 11104-38-4 Chem. Abstr. Name: Vitamin K1 Phylloquinone Chem. Abstr. Serv. Reg. No.: 84-80-0 Deleted CAS Reg. Nos.: 10485-69-5; 15973-57-6; 50926-17-5 417