Amiodarone Hydrochloride Injection contains amiodarone HCl (C25H29I2NO3Ã‚Â·HCl), … Amiodarone Hydrochloride Injection is a sterile clear, pale-yellow …
AMIODARONE HYDROCHLORIDE INJECTION
with Amiodarone Hydrochloride Injection. Clinically significant hypotension during infusions was seen most often in the first several hours of treatment and was not dose related, but appeared to be related to the rate of infusion. Hypotension necessitating alterations in Amiodarone Hydrochloride Injection therapy was reported in 3% of patients, with permanent discontinuation required in less than 2% of patients. Hypotension should be treated initially by slowing the infusion; additional standard therapy may be needed, including the following: vasopressor drugs, positive inotropic agents, and volume expansion. The initial rate of infusion should be monitored closely and should not exceed that prescribed in DOSAGE AND ADMINISTRATION. In some cases, hypotension may be refractory resulting in fatal outcome (see ADVERSE REACTIONS, Postmarketing Reports).