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for cholecalciferol in dogs is about 88 mg/kg, or 3520000 IU/kg. … 110-pound adult taking 176000000 IU or 440000 of the 400 unit cholecalciferol capsules. …

The Truth About Vitamin D Toxicity
Is vitamin D toxic? Not if we take the same amount nature intended when we go out in the sun. Vitamin D supplementation, 25-hydroxyvitamin D concentration, and safety. Vieth attempted to dispel unwarranted fears in medical community of physiological doses of vitamin D in 1999 with his exhaustive and well-written review.

Vitamin D Toxicity Fear Unwarranted
His conclusions: fear of vitamin D toxicity is unwarranted, and such unwarranted fear, bordering on hysteria, is rampant in the medical profession. Efficacy and safety of vitamin D3 intake exceeding the lowest observed adverse effect level. Even Ian Monroe, the chair of the relevant IOM committee, wrote to the Journal to compliment Vieth’s work and to promise his findings will be considered at the time of a future Institute of Medicine review. Derivation of tolerable upper intake levels of nutrients. That was more than two years ago. In 1999, Vieth indirectly asked the medical community to produce any evidence 10,000 units of vitamin D a day was toxic, saying “Throughout my preparation of this review, I was amazed at the lack of evidence supporting statements about the toxicity of moderate doses of vitamin D.” He added: “If there is published evidence of toxicity in adults from an intake of 250 ug (10,000 IU) per day, and that is verified by the 25(OH)D concentration, I have yet to find it.” Vitamin D supplementation, 25-hydroxyvitamin D concentration, and safety.

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